Trisha Shetty (Editor)

Oleoyl (acyl carrier protein) hydrolase

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EC number
  
3.1.2.14

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
68009-83-6

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, an oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14) is an enzyme that catalyzes the chemical reaction

oleoyl-[acyl-carrier-protein] + H2O [acyl-carrier-protein] + oleate

Thus, the two substrates of this enzyme are [[oleoyl-[acyl-carrier-protein]]] and H2O, whereas its two products are acyl-carrier-protein and oleate.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is oleoyl-[acyl-carrier-protein] hydrolase. Other names in common use include acyl-[acyl-carrier-protein] hydrolase, acyl-ACP-hydrolase, acyl-acyl carrier protein hydrolase, oleoyl-ACP thioesterase, and oleoyl-acyl carrier protein thioesterase. This enzyme participates in fatty acid biosynthesis.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2OWN and 2PFF.

References

Oleoyl-(acyl-carrier-protein) hydrolase Wikipedia