Old Mission House

The Old Mission House is a historic Episcopal church mission house in Fort Yukon, Alaska. It was constructed in 1925 as part of a Native American mission. It was the third mission house built on the site, nearly duplicating one built in 1914 and destroyed by fire. The house is a 2-1/2 story log structure in an L shape, with interior rooms constructed by frame construction. The building was the center of the religious mission, which provided educational and health services to the local Native population. This building was used as a school, providing boarding space for students from distant areas. In 1957 the building was adapted for use as the medical clinic after the previous clinic building was closed and later torn down.

The building added to the National Register of Historic Places in 1978.