Symbol TNFSF4 HUGO 11934 RefSeq NM_003326 | Entrez 7292 OMIM 603594 | |
Alt. symbols TXGP1, OX-40L, gp34, CD252 | ||
OX40L is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. OX40L has also been designated CD252 (cluster of differentiation 252).
Various single nucleotide polymorphisms (SNPs) of the OX40L gene have been identified. For some of them association with systemic lupus erythematosus has been reported: No association with occurrence of atherosclerosis has been found.
References
OX40L Wikipedia(Text) CC BY-SA