Aliases NUP88 Human Mouse Ensembl ENSG00000108559 | Species Human Entrez 4927 | |
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External IDs MGI: 104900 HomoloGene: 1901 GeneCards: NUP88 | ||
Nucleoporin 88 (Nup88) is a protein that in humans is encoded by the NUP88 gene.
Contents
Function
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias.
Interactions
NUP88 has been shown to interact with NUP98.
References
Nucleoporin 88 Wikipedia(Text) CC BY-SA