Nowell is the surname of:
Alexander Nowell (c. 1507–1602), Anglican Puritan theologian and clergyman; dean of St Paul's
Andrew Nowell, MP for Rutland
Ben Nowell (born 1985), New Zealand rugby union player
Bradley Nowell (1968-1996), lead singer and guitarist of the ska punk band Sublime
Howard Wilbert Nowell (1872–1940), instructor in pathology at Boston University and a pioneering cancer researcher
Increase Nowell (1590-1655), colonial administrator, original patentee of the Massachusetts Bay Company, founder of Charlestown, Massachusetts, and first ruling elder of the First Church in Charlestown
Jack Nowell (born 1993), rugby union player
Laurence Nowell, two English cousins often confused with each other, one an antiquarian, cartographer and scholar (c. 1515–c. 1571), the other a churchman (died 1576)
Louis R. Nowell (1915–2009), Los Angeles city fire captain and politician
Mel Nowell (born 1940), National Basketball Association player
Peter Nowell (born 1928), cancer researcher and professor
Thomas Nowell (1730?–1801), English clergyman, historian and religious controversialist
Wedgwood Nowell (1878–1957), American film actor
William Nowell (1880–1968), a British mycologist