ATC code none PubChem CID 3034416 ChemSpider 21248347 Molar mass 661.784 g/mol | CAS Number 105618-26-6 IUPHAR/BPS 1642 UNII 36OOQ86QM1 | |
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How to pronounce norbinaltorphimine
Norbinaltorphimine (nor-BNI or nBNI) is an opioid antagonist used in scientific research. It is one of the few opioid antagonists available that is highly selective for the κ-opioid receptor, and blocks this receptor without affecting the μ- or δ-opioid receptors, although it has less selectivity in vivo than when used in isolated tissues. nor-BNI blocks the effects of κ-opioid agonists in animal models, and produces antidepressant effects.
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