Aliases NID1, NID, nidogen 1 Human Mouse Ensembl ENSG00000116962 | Species Human Entrez 4811 | |
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External IDs OMIM: 131390 MGI: 97342 HomoloGene: 1878 GeneCards: NID1 | ||
Nidogen-1 (NID-1), formerly known as entactin, is a protein that in humans is encoded by the NID1 gene. Both nidogen-1 and nidogen-2 are essential components of the basement membrane alongside other components such as type IV collagen, proteoglycans (heparan sulfate and glycosaminoglycans), laminin and fibronectin.
Contents
Function
Nidogen-1 is a member of the nidogen family of basement membrane glycoproteins. The protein interacts with several other components of basement membranes. Structurally it (along with perlecan) connects the networks formed by collagens and laminins to each other. It may also play a role in cell interactions with the extracellular matrix.
Interactions
Nidogen-1 has been shown to interact with FBLN1.
References
Nidogen-1 Wikipedia(Text) CC BY-SA