Newcomb is a surname. Notable people with the name include:
Anthony Newcomb (born 1941), American musicologistBernard A. Newcomb, American businessperson and philanthropist, co-founder of E*TRADEBryant B. Newcomb (1867–1945), American politicianCarman A. Newcomb (1830–1902), American politician, lawyer and judgeCyrenius A. Newcomb, Sr. (1837–1915), American businessman, reformer, and philanthropistDeborah Newcomb (born 1954), member of the Ohio House of RepresentativesGeorge Newcomb (1866–1895), outlaw of the American Old West and member of the Wild BunchFrank Newcomb (1846–1934), commodore in the United States Revenue Cutter ServiceHarvey Newcomb (1803–1863), American clergyman and writerHoratio C. Newcomb (1821–1882), American attorney, judge, and politicianJames Pearson Newcomb (1837–1907), journalist and Secretary of State of TexasJohn Lloyd Newcomb (1881–1954), American educatorJosephine Louise Newcomb (1816–1901), American philanthropist whose grant founded H. Sophie Newcomb Memorial CollegeJosiah T. Newcomb (1868–1944), New York politicianMary Newcomb (1893–1966), American actressPhilip Newcomb (born 1950s), American software engineerRexford Newcomb (1886–1968), American academician, architect, and authorRichard Newcomb, American war correspondentRobert Newcomb, fantasy writerRonda Storms (born Ronda Rehnell Newcomb, 1965), American politicianSean Newcomb (born 1993), American baseball pitcherSimon Newcomb (1835–1909), Canadian astronomer and mathematicianWilliam Newcomb (died 1999), American professor and theoretical physicist who devised Newcomb's paradoxWesley Newcomb (1818–1892), American malacologist (studier of mollusks)