Symbol NMUR1 Entrez 10316 OMIM 604153 | Alt. symbols GPR66 HUGO 4518 RefSeq NM_006056 | |
The neuromedin U receptors are two G-protein coupled receptors which bind the neuropeptide hormones neuromedin U and neuromedin S. There are two subtypes of the neuromedin U receptor, each encoded by a separate gene (NMUR1, NMUR2).
Contents
Selective Ligands
Neuromedin U is an agonist at both the NMU1 and NMU2 subtypes, while neuromedin S is selective for NMU2, and is a more potent agonist at this subtype than neuromedin U. Several other peptide and non-peptide ligands are also available for the NMU receptors.
Agonists
Antagonists
References
Neuromedin U receptor Wikipedia(Text) CC BY-SA