Rahul Sharma (Editor)

Network of Cancer Genes

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Research center
  
King's College London

Release date
  
October 2015

Version
  
5.0

Primary citation
  
PMID 26516186

Description
  
A web resource on systems-level properties of cancer genes

Network of Cancer Genes is a web resource on systems-level properties of cancer genes and oncomiRs.

Contents

NCG reports information on duplicability, orthology, evolutionary appearance, interactions, function, expression of a manually curated list of 1,571 protein-coding cancer genes. Cancer genes are genes with a driver role in the onset of human cancer upon mutations of their sequence and/or amplifications of their genomic locus. The list of cancer genes is derived from the union of the Cancer Gene Census (known cancer genes) and from the results of 77 whole genome or whole exome cancer-resequencing screenings (candidate cancer genes). In addition, the database also annotates possible false positives, defined as candidate cancer genes whose association with cancer is likely to be spurious. NCG is also available as a smart phone application for Android.

Cancer Types

NCG currently stores information on the following 23 cancer types:

  • Cholangiocarcinoma
  • Glioblastoma
  • Head and neck squamous cell carcinoma
  • Leukemia
  • Lymphoma
  • Medulloblastoma
  • Melanoma
  • Myelodysplasia
  • Myeloma
  • Neuroblastoma
  • Oligodendroglioma
  • Sarcoma
  • Bladder
  • Breast
  • Colorectal
  • Endometrium
  • Gastric
  • Kidney
  • Liver
  • Lung
  • Ovarian
  • Pancreas
  • Prostate
  • Old Versions

  • NCG3.0
  • NCG2.0
  • References

    Network of Cancer Genes Wikipedia