Nathusius is a surname. Notable people with the surname include:
Annemarie von Nathusius (1874-1926), German novelistHermann von Nathusius (1809–1879), German animal breederJohann Gottlob Nathusius (1760–1835), German industrialistMarie Nathusius (1817-1857), German novelistPhilipp von Nathusius (publisher) (1815-1872), German publisherSuzanna von Nathusius, Polish child film actorThomas von Nathusius (1866–1904), German landscape and animal painterSusanne von Nathusius (1850–1929), portrait painter