Entrez 10204 | Ensembl ENSG00000102898 | |
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Aliases NUTF2, NTF2, PP15, NTF-2, nuclear transport factor 2 External IDs MGI: 1915301 HomoloGene: 110745 GeneCards: NUTF2 |
Function
The protein encoded by this gene is a cytosolic factor that facilitates protein transport into the nucleus. It interacts with the nuclear pore complex glycoprotein p62. This encoded protein acts at a relative late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. It is thought to be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import.
Interactions
NUTF2 has been shown to interact with Nucleoporin 62{ and RAN.
References
NUTF2 Wikipedia(Text) CC BY-SA