CAS Number 324523-20-8 IUPHAR/BPS 716 ECHA InfoCard 100.230.440 | PubChem CID 6918446 ChemSpider 5293643 Formula C24H25ClN2O2 | |
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NPS-2143 (SB-262,470A) is a calcilytic drug which acts as an antagonist at the Calcium-sensing receptor (CaSR), and consequently stimulates release of parathyroid hormone. Calcilytic drugs have been researched as potential treatments for osteoporosis, and as the first such compound developed, NPS-2143 is still widely used in research into the CaSR receptor as well as design of newer calcilytic agents.
References
NPS-2143 Wikipedia(Text) CC BY-SA