Rahul Sharma (Editor)

NPAS2

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Species
  
Human

Entrez
  
4862

Human
  
Mouse

Ensembl
  
ENSG00000170485

NPAS2

Aliases
  
NPAS2, MOP4, PASD4, bHLHe9, neuronal PAS domain protein 2

External IDs
  
OMIM: 603347 MGI: 109232 HomoloGene: 1887 GeneCards: NPAS2

Neuronal PAS domain-containing protein 2 is a protein that in humans is encoded by the NPAS2 gene.

Contents

Function

The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. A similar mouse protein may play a regulatory role in the acquisition of specific types of memory. It also may function as a part of a molecular clock operative in the mammalian forebrain.

NPAS2 has been shown to be analogous to the function of CLOCK in CLOCK deficient mice.

Interactions

NPAS2 has been shown to interact with:

  • ARNTL,
  • EP300, and
  • Retinoic acid receptor alpha.
  • References

    NPAS2 Wikipedia