Trisha Shetty (Editor)

NOBOX

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Species
  
Human

Entrez
  
135935

Human
  
Mouse

Ensembl
  
ENSG00000106410

Aliases
  
NOBOX, OG-2, OG2, OG2X, POF5, TCAG_12042, NOBOX oogenesis homeobox

External IDs
  
MGI: 108011 HomoloGene: 51066 GeneCards: NOBOX

Homeobox protein NOBOX, also known as newborn ovary homeobox protein, is a protein that in humans is encoded by the NOBOX gene.

Contents

Function

NOBOX is a homeobox gene that is preferentially expressed in oocytes. In mice, it is essential for folliculogenesis and regulation of oocyte-specific genes.

Clinical significance

A mutation in the NOBOX gene is associated with premature ovarian failure.

References

NOBOX Wikipedia