Species Human Entrez 4831 | Human Mouse Ensembl ENSG00000243678 | |
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Aliases NME2, NDKB, NDPK-B, NDPKB, NM23-H2, NM23B, PUF, NME/NM23 nucleoside diphosphate kinase 2 External IDs MGI: 97356 HomoloGene: 133879 GeneCards: NME2 | ||
Nucleoside diphosphate kinase B is an enzyme that in humans is encoded by the NME2 gene.
Contents
Function
Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. Co-transcription of this gene and the neighboring upstream gene (NME1) generates naturally occurring transcripts (NME1-NME2) which encode a fusion protein consisting of sequence sharing identity with each individual gene product.
Interactions
NME2 has been shown to interact with NME3 and HERC5.
References
NME2 Wikipedia(Text) CC BY-SA