Supriya Ghosh (Editor)

NME2

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Species
  
Entrez
  
4831

Human
  
Ensembl
  
ENSG00000243678

NME2 httpsuploadwikimediaorgwikipediacommonsthu

Aliases
  
NME2, NDKB, NDPK-B, NDPKB, NM23-H2, NM23B, PUF, NME/NM23 nucleoside diphosphate kinase 2

External IDs
  
MGI: 97356 HomoloGene: 133879 GeneCards: NME2

Nucleoside diphosphate kinase B is an enzyme that in humans is encoded by the NME2 gene.

Contents

Function

Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. Co-transcription of this gene and the neighboring upstream gene (NME1) generates naturally occurring transcripts (NME1-NME2) which encode a fusion protein consisting of sequence sharing identity with each individual gene product.

Interactions

NME2 has been shown to interact with NME3 and HERC5.

References

NME2 Wikipedia


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