Species Human Entrez 4795 | Human Mouse Ensembl n/a | |
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Aliases NFKBIL1, IKBL, LST1, NFKBIL, NFKB inhibitor like 1 External IDs MGI: 1340031 HomoloGene: 3671 GeneCards: NFKBIL1 | ||
NF-kappa-B inhibitor-like protein 1 is a protein that in humans is encoded by the NFKBIL1 gene.
Contents
Function
This gene encodes a divergent member of the I-kappa-B family of proteins. Its function is unclear. The gene lies within the major histocompatibility complex (MHC) class I region on chromosome 6.
Model organisms
Model organisms have been used in the study of NFKBIL1 function. A conditional knockout mouse line called Nfkbil1tm1a(KOMP)Wtsi was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping
References
NFKBIL1 Wikipedia(Text) CC BY-SA