Species Human Entrez 4761 | Human Mouse Ensembl ENSG00000171532 | |
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Aliases NEUROD2, NDRF, bHLHa1, neuronal differentiation 2 External IDs MGI: 107755 HomoloGene: 4489 GeneCards: NEUROD2 | ||
Neurogenic differentiation factor 2 is a protein that in humans is encoded by the NEUROD2 gene.
Contents
Function
This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.
Interactions
NEUROD2 has been shown to interact with Protein kinase N1.
References
NEUROD2 Wikipedia(Text) CC BY-SA