Species Human Entrez 10825 | Human Mouse Ensembl ENSG00000162139 | |
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Aliases NEU3, SIAL3, neuraminidase 3 (membrane sialidase), neuraminidase 3, membrane sialidase External IDs MGI: 1355305 HomoloGene: 4847 GeneCards: NEU3 |
Sialidase-3 is an enzyme that in humans is encoded by the NEU3 gene.
Contents
Function
This gene product belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. It is localized in the plasma membrane, and its activity is specific for gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer.
Interactions
NEU3 has been shown to interact with Grb2.
References
NEU3 Wikipedia(Text) CC BY-SA