Supriya Ghosh (Editor)

NEU3

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Species
  
Human

Entrez
  
10825

Human
  
Mouse

Ensembl
  
ENSG00000162139

NEU3

Aliases
  
NEU3, SIAL3, neuraminidase 3 (membrane sialidase), neuraminidase 3, membrane sialidase

External IDs
  
MGI: 1355305 HomoloGene: 4847 GeneCards: NEU3

Sialidase-3 is an enzyme that in humans is encoded by the NEU3 gene.

Contents

Function

This gene product belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. It is localized in the plasma membrane, and its activity is specific for gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer.

Interactions

NEU3 has been shown to interact with Grb2.

References

NEU3 Wikipedia