Of this group, several spaceflight firsts were achieved:
First American-born Hispanic astronaut and first Hispanic shuttle pilot and commander: Sidney Gutierrez (June 5, 1991, STS-40)
First International Space Station commander: William Shepherd (October 31, 2000, Expedition 1)
First person to command five space missions and tallest person in space: James Wetherbee (November 23, 2002, STS-113)
First submariner in space: Michael McCulley (October 18, 1989, STS-34)
Kenneth D. Cameron (born 1949), U.S. Marine Corps (3 flights)
STS-37
Atlantis - April 1991 - Pilot - Compton Gamma Ray Observatory deployment
STS-56
Discovery - April 1993 - Commander - ATLAS-2, solar observation experiments, first radio contact between the Space Shuttle and
Mir
STS-74
Atlantis - November 1995 - Commander - Second
Mir docking, fourth Shuttle-Mir mission
John H. Casper (born 1943), U.S. Air Force (4 flights)
STS-36
Atlantis - February 1990 - Pilot - Classified United States Department of Defense mission, deployed USA-53 (Misty)
STS-54
Endeavour - January 1993 - Commander - TDRS-6 deployment
STS-62
Columbia - March 1994 - Commander - USMP-02 microgravity experiment package and OAST-2 payload
STS-77
Endeavour - May 1996 - Commander - SPACEHAB mission
Frank L. Culbertson, Jr. (born 1949), U.S. Navy (5 flights)
STS-38
Atlantis - November 1990 - Pilot - Classified United States Department of Defense mission, spy satellite deployment
STS-51
Discovery - September 1993 - Commander - Advanced Communications Technology Satellite deployment
STS-105
Discovery - August 2001 - Mission Specialist - International Space Station mission, crew rotation and delivery of MPLM
Leonardo
ISS Expedition 3 - August–December 2001 - Commander
STS-108
Endeavour - December 2001 - Mission Specialist - International Space Station mission, crew rotation and delivery of MPLM
Raffaello
Sidney M. Gutierrez (born 1951), U.S. Air Force (2 flights)
STS-40
Columbia - June 1991 - Pilot - Spacelab mission
STS-59
Endeavour - April 1994 - Commander - SRL-1 radar observations
L. Blaine Hammond, Jr. (born 1952), U.S. Air Force (2 flights)
STS-39
Discovery - April 1991 - Pilot - First unclassified United States Department of Defense mission
STS-64
Discovery - September 1994 - Pilot - Earth and solar observations, first untethered spacewalk since STS-51-A
Michael J. McCulley (born 1943), U.S. Navy (1 flight)
STS-34
Atlantis - October 1989 - Pilot - Deployment of Galileo orbiter and probe to Jupiter
James D. "Wxb" Wetherbee (born 1952), U.S. Navy (6 flights)
STS-32
Columbia - January 1990 - Pilot - Long Duration Exposure Facility retrieval, deployment of SYNCOM IV-F5
STS-52
Columbia - October 1992 - Commander - LAGOES-II deployment, USMP-01 microgravity experiment package
STS-63
Discovery - February 1995 - Commander - First rendezvous of the Space Shuttle and
Mir, second Shuttle-Mir mission, first Shuttle mission with female Pilot
STS-86
Atlantis - September 1997 - Commander - Seventh
Mir docking
STS-102
Discovery - March 2001 - Commander - International Space Station mission, crew rotation and delivery of MPLM
Leonardo
STS-113
Endeavour - November 2002 - Commander - International Space Station mission, crew rotation and installment of P1 truss, last successful Shuttle mission before the
Columbia disaster
James C. Adamson (born 1946), U.S. Army (2 flights)
STS-28
Columbia - August 1989 - Mission Specialist - Classified United States Department of Defense mission, USA-40 and USA-41 deployments
STS-43
Atlantis - August 1991 - Mission Specialist - TDRS-5 deployment
Ellen S. Baker (born 1953), Physician (3 flights)
STS-34
Atlantis - October 1989 - Mission Specialist - Deployment of Galileo orbiter and probe to Jupiter
STS-50
Columbia - June 1992 - Mission Specialist - USML-1 microgravity laboratory mission, first use of Extended Duration Orbiter package and first landing of
Columbia at Kennedy Space Center
STS-71
Atlantis - June 1995- Mission Specialist - First docking with
Mir, third Shuttle-Mir mission,
Mir crew rotation
Mark N. Brown (born 1951), U.S. Air Force (2 flights)
STS-28
Columbia - August 1989 - Mission Specialist - Classified United States Department of Defense mission, USA-40 and USA-41 deployments
STS-48
Discovery - September 1991 - Mission Specialist - Upper Atmosphere Research Satellite deployment
Manley L. "Sonny" Carter, Jr. (1947-1991), U.S. Navy (1 flight)
STS-33
Discovery - November 1989 - Mission Specialist - Classified United States Department of Defense mission, USA-48 deployment, first night launch since
Challenger disaster
Marsha S. Ivins (born 1951), Engineer (5 flights)
STS-32
Columbia - January 1990 - Mission Specialist - Long Duration Exposure Facility retrieval, deployment of SYNCOM IV-F5
STS-46
Atlantis - July 1992 - Mission Specialist - European Retrievable Carrier deployment, tethered satellite experiments
STS-62
Columbia - March 1994 - Mission Specialist - USMP-02 microgravity experiment package and OAST-2 payload
STS-81
Atlantis - January 1997 - Mission Specialist - Third
Mir docking, fifth Shuttle-Mir mission,
Mir crew rotation
STS-98
Atlantis - February 2001 - Mission Specialist - International Space Station mission, installment of Destiny Laboratory Module
Mark C. Lee (born 1952), U.S. Air Force (4 flights)
STS-30
Atlantis - May 1989 - Mission Specialist - Deployment of Magellan probe to Venus
STS-47
Endeavour - September 1992 - Payload Commander - Spacelab mission, first Japanese astronaut to fly on the Shuttle, first African-American woman in space, first married couple in space
STS-64
Discovery - September 1994 - Mission Specialist - Earth and solar observations, first untethered spacewalk since STS-51-A
STS-82
Discovery - February 1997 - Mission Specialist - Second Hubble Space Telescope servicing mission
G. David Low (1956-2008), Engineer (3 flights)
STS-32
Columbia - January 1990 - Mission Specialist - Long Duration Exposure Facility retrieval, deployment of SYNCOM IV-F5
STS-43
Atlantis - August 1991 - Mission Specialist - TDRS-5 deployment
STS-57
Endeavour - June 1993 - Mission Specialist - European Retrievable Carrier retrieval, SPACEHAB mission
William M. Shepherd (born 1949), U.S. Navy (6 flights)
STS-27
Atlantis - December 1988 - Mission Specialist - Classified United States Department of Defense mission, USA-34 (Lacrosse-1) deployment
STS-41
Discovery - October 1990 - Mission Specialist - Deployment of Ulysses probe into polar orbit of the Sun
STS-52
Columbia - October 1992 - Mission Specialist - LAGOES-II deployment, USMP-01 microgravity experiment package
Soyuz TM-31 - October 2000 - Flight Engineer - First Soyuz spacecraft to dock with the International Space Station
ISS Expedition 1 - November 2000-March 2001 - Commander - First long-duration International Space Station crew
STS-102
Discovery - March 2001 - Mission Specialist - International Space Station mission, crew rotation and delivery of MPLM
Leonardo
Kathryn C. Thornton (born 1952), Physicist (4 flights)
STS-33
Discovery - November 1989 - Mission Specialist - Classified United States Department of Defense mission, USA-48 deployment, first night launch since
Challenger disaster
STS-49
Endeavour - May 1992 - Mission Specialist - Maiden flight of
Endeavour, Intelsat 603 retrieval and relaunch
STS-61
Endeavour - December 1993 - Mission Specialist - First Hubble Space Telescope servicing mission
STS-73
Columbia - October 1995 - Mission Specialist - USML-2 microgravity laboratory mission
Charles Veach (1944-1995), U.S. Air Force (2 flights)
STS-39
Discovery - April 1991 - Mission Specialist - First unclassified United States Department of Defense mission
STS-52
Columbia - October 1992 - Mission Specialist - LAGOES-II deployment, USMP-01 microgravity experiment package