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N acyl D amino acid deacylase

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EC number
  
3.5.1.81

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
65979-42-2

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a N-acyl-D-amino-acid deacylase (EC 3.5.1.81) is an enzyme that catalyzes the chemical reaction

N-acyl-D-amino acid + H2O an acid + D-amino acid

Thus, the two substrates of this enzyme are N-acyl-D-amino acid and H2O, whereas its two products are acid and D-amino acid.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-acyl-D-amino acid amidohydrolase. It employs one cofactor, zinc.

Structural studies

As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes 1M7J, 1RJP, 1RJQ, 1RJR, 1RK5, 1RK6, 1V4Y, and 1V51.

References

N-acyl-D-amino-acid deacylase Wikipedia