Samiksha Jaiswal (Editor)

N Phenethyl 4 piperidinone

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Abbreviations
  
NPP

Molar mass
  
203.28 g/mol

Formula
  
C13H17NO

Density
  
1.057 g/cm³

N-Phenethyl-4-piperidinone httpsuploadwikimediaorgwikipediacommonsthu

N-Phenethyl-4-piperidinone (NPP) is a derivative of 4-piperidinone with the molecular formula C13H17NO. 4-Piperidinone is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs such as fentanyl.

Contents

Because of its possible use in the illicit manufacture of fentanyl, NPP was placed onto the list of controlled chemicals in the USA in 2007, and possession and sales of this compound are now restricted.

Preparation

N-Phenethyl-4-piperidinone can be prepared from 4-piperidinone and phenethyl bromide in biphasic conditions with a variety of phase transfer catalysts.

Derivatives

  1. Fentanyl
  2. Carfentanil
  3. PEPAP
  4. Fenspiride
  5. Propinetidine

References

N-Phenethyl-4-piperidinone Wikipedia