N (long chain acyl)ethanolamine deacylase

In enzymology, a N-(long-chain-acyl)ethanolamine deacylase (EC 3.5.1.60) is an enzyme that catalyzes the chemical reaction

N-(long-chain-acyl)ethanolamine + H₂O ⇌ a long-chain carboxylate + ethanolamine

Thus, the two substrates of this enzyme are N-(long-chain-acyl)ethanolamine and H₂O, whereas its two products are long-chain carboxylate and ethanolamine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-(long-chain-acyl)ethanolamine amidohydrolase. Other names in common use include N-acylethanolamine amidohydrolase, and acylethanolamine amidase.