Group Group IV ((+)ssRNA) Family Coronaviridae Genus Betacoronavirus Higher classification Betacoronavirus | Order Nidovirales Subfamily Coronavirinae Scientific name Murine coronavirus Rank Species | |
Similar Coronaviridae, Transmissible gastroenteritis coronavirus, Avian infectious bronchitis, Bovine coronavirus, Nidovirales | ||
Mouse hepatitis virus is a virus of the family Coronaviridae, genus Betacoronavirus.
The Murine coronavirus, Mouse hepatitis virus (MHV), is a coronavirus that causes an epidemic murine illness with high mortality, especially among colonies of laboratory mice. Prior to the discovery of SARS-CoV, MHV had been the best-studied coronavirus both in vivo and in vitro as well as at the molecular level. Some strains of MHV cause a progressive demyelinating encephalitis in mice which has been used as a murine model for multiple sclerosis. Significant research efforts have been focused on elucidating the viral pathogenesis of these animal coronaviruses, especially by virologists interested in veterinary and zoonotic diseases.
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Mouse hepatitis virus Wikipedia(Text) CC BY-SA