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Mostafa Ronaghi

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Name
  
Mostafa Ronaghi

Role
  
Researcher

Mostafa Ronaghi aimsstanfordeduimagesspeakersMostafaRonaghijpg
Education
  
Royal Institute of Technology (1998)

Books
  
Array-Based Pyrosequencing Technology: Chapter 2 from Genome Sequencing Technology & Algorithms

Organizations founded
  
Nextbio, Avantome Inc, Biotage, ParAllele Bioscience

Similar People
  
Pal Nyren, Ronald W Davis, Nader Pourmand, Helmy Eltoukhy, Juan G Santiago

1/30/13 - Mostafa Ronaghi, "Bridging the gap between science, innovation and market"


Mostafa Ronaghi (born 1968) is an Iranian molecular biologist, specializing in DNA sequencing methodology. He earned his Ph.D. from the Royal Institute of Technology in Sweden in 1998.

Contents

As of 2008, he is the Chief Technology Officer and Senior Vice President at Illumina. Prior to this position, he was a principal investigator and Senior Research Associate at the Stanford Genome Technology Center at Stanford University, focusing on developing analytical techniques for molecular diagnostics.

He is principal investigator for several grants including grants from the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health for the development of array-based Pyrosequencing.

He is a co-inventor (with Pal Nyren) of pyrosequencing technology and co-founded Pyrosequencing AB in 1997 (renamed to Biotage in 2003), and co-invented Molecular Inversion Probe assay and co-founded ParAllele BioScience to develop this multiplexed technology for genetic testing. ParAllele was acquired by Affymetrix in May 2005. In 2005, he co-founded NextBio, a search engine for life science data that was acquired by Illumina in 2013. He also serves on the board of directors of IntegenX and Aurora Biofuels. In 2008 he co-founded Avantome, a DNA sequencing company acquired by Illumina July 2008.

Publications

Among his approximately 50 peer-reviewed journal articles are the publications describing Pyrosequencing and Molecular Inversion Probe assays and other techniques:

  • Absalan, F; Ronaghi, M (2007). "Molecular inversion probe assay". Methods in Molecular Biology 396: 315–30. doi:10.1007/978-1-59745-515-2_20. PMID 18025701. 
  • Hardenbol, P; Baner, J; Jain, M; Nilsson, M; Namsaraev, EA; Karlin-Neumann, GA; Fakhrai-Rad, H; Ronaghi, M; Willis, TD; Landegren, U; Davis, RW (Jun 2003). "Multiplexed genotyping with sequence-tagged molecular inversion probes". Nature Biotechnology 21 (6): 673–8. doi:10.1038/nbt821. PMID 12730666. 
  • "Prediction of protein orientation upon immobilization on biological and nonbiological surfaces". Proceedings of the National Academy of Sciences 103 (40): 14773–8. Oct 2006. doi:10.1073/pnas.0605841103. PMC 1576295. PMID 17001006. 
  • Ronaghi, M (Jan 2001). "Pyrosequencing sheds light on DNA sequencing". Genome Research 11 (1): 3–11. doi:10.1101/gr.11.1.3. PMID 11156611. 
  • Ronaghi, M; Uhlen, M; Nyren, P (Jul 1998). "A sequencing method based on real-time pyrophosphate". Science 281 (5375): 363–365. doi:10.1126/science.281.5375.363. PMID 9705713. 
  • Ronaghi, M; Karamohamed, S; Pettersson, B; Uhlen, M; Nyren, P (Nov 1996). "Real-time DNA sequencing using detection of pyrophosphate release". Analytical Biochemistry 242 (1): 84–9. doi:10.1006/abio.1996.0432. PMID 8923969. 
  • He also holds about 20 patents.

    References

    Mostafa Ronaghi Wikipedia