Rahul Sharma (Editor)

Molybdopterin synthase

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EC number
  
2.8.1.12

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

Molybdopterin synthase (EC 2.8.1.12, MPT synthase) is an enzyme required to synthesize molybdenum cofactor (MoCo) from precursor Z (now known as cyclic pyranopterin monophosphate). This enzyme catalyses the following chemical reaction

cyclic pyranopterin monophosphate + 2 [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH2-C(O)SH + H2O ⇌ molybdopterin + 2 molybdopterin-synthase sulfur-carrier protein

It is heterodimeric and coded for by the MOCS2 gene.

References

Molybdopterin synthase Wikipedia
(Text) CC BY-SA