Hulisani was born in the former homeland of Venda, in South Africa, in 1979.
Throughout his early life, there is no record to imply any interest in politics. It was only during high school, when Hulisani became the president of the SRC of Guvhukuvhu High School, in the village of Phiphidi in the former Venda; that it became apparent. His stay at the helm of the SRC was marked by a renewed politicalization of students who before had quietly lead their student lives. Unconfirmed reports places, a number of student marches in that school, during his reign as president of the SRC.
It is not clear as to when did Hulisani became a member of the PAC and PAYCO in particular.
But before serving as the president of PAYCO, Hulisani held a number of positions within the ranks of the party including its student wing, PASMA and branches. He also served as the Secretary General of PAYCO before becoming the President
Hulisani was also one of the voices that opposed the Floor-Crossing policy, championed and legislated by the ANC government, which allowed party representatives in parliament to move to another party while keeping their seat in parliament.
Hulisani also worked as a Researcher for the Limpopo Legislature in 2003, working with Maxwel Nemadzivhanani., then Provincial chairman of PAC in Limpopo Province.
At a PAYCO National Congress held in Durban, under the theme "Mobilizing Youth Power to Build Socialism and African Unity", Hulisani was elected President of PAYCO succeeding its former president Sbusiso Xaba.
On March 2008, he condemned the racist video made by students from the Free State University. Of the acts portrayed in the video he said they "makes a mockery of the struggle against apartheid settler colonialism,"
On 30 May 2009, Hulisani convened the 1st Mayihlome Annual Lecture, which was addressed by the former President of PAYCO, Mashao Matome.The lecture was used as a forum to discuss a new programme adopted by PAYCO called IOTA, which is aimed at repositioning the PAC. On the same occasion an online News publication called "Mayihlome" was launched on WordPress, Hulisani currently serves as its Chief Editor.
At the PAYCO Kimberly National Congress held in November 2009, Hulisani was succeeded by Ndebele Linda as president of PAYCO
Hulisani, in his capacity as an official of PAYCO, has a relationship with the ASI, an international body of socialists who pursue a pan-African agenda. In 2006, he had a meeting with ASI Chairman Omali Yeshitela and others, on his visit to South Africa.
On 30th May 2009 Hulisani, as President of the PAYCO launched Mayihlome News, an online Pan-Africanist journal. Initially Mayihlome News was hosted on the free Wordpress platform and in July 2014 it was moved to a self hosted platform. Mayihlome News has attracted Pan-Africanists world wide giving insight into the Pan-Africanist political landscape in South Africa.
A number of controversies has followed the election of Hulisani as president of PAYCO. Some even calling them politically suicidal:
9 January 2008: Hulisani, in a statement, called for the resignation of PAC president Lethlapa Mphahlele. This position was met with strong objection among the leadership of the PAC, who even mentioned that PAYCOdid not qualify, as a component structure, to call for the resignation of the president of the organisation. Some provincial PAYCOleaders distanced themselves from the decision and the pronouncement made by Hulisani, some even calling it unilateral. However Hulisani insisted that the decision was not taken by his person but by the NEC of PAYCO, including the provincial leaders.
30 January 2009: a communication was made by the PAYCO NEC, to the members, on the decision to boycott the 2009 General Elections of South Africa so as to refuse the PAC votes. This position received some opposition from within the Pan Africanist Youth Congress of Azania, and was also against the position of PAC, as it participated in the elections.
Hulisani Holds an LLB(hons) from Unisa where he also completed his BJuris.