Puneet Varma (Editor)

Mitochondrial ferritin

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Species
  
Human

Entrez
  
94033

Human
  
Mouse

Ensembl
  
ENSG00000181867

Mitochondrial ferritin

Aliases
  
FTMT, MTF, Mitochondrial ferritin, ferritin mitochondrial

External IDs
  
MGI: 1914884 HomoloGene: 110661 GeneCards: FTMT

Mitochondrial ferritin is a ferroxidase enzyme that in humans is encoded by the FTMT gene.

It is classified as a metal-binding protein which is located within the mitochondria. After the protein is taken up by the mitochondria it can be processed into a mature protein and assemble functional ferritin shells.

Structure

Its structure was determined at 1.70 Å through the use of X-ray diffraction and contains 182 residues. It is 67% helical. The Ramachandran plot shows that the structure of mitochondrial ferritin is mainly alpha helical with a low prevalence of beta sheets.

References

Mitochondrial ferritin Wikipedia