Puneet Varma (Editor)

Mir 451 microRNA

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Covid-19
Symbol  mir-451
miRBase family  MIPF0000148
OMIM  612071
Rfam  RF00722
HUGO  MIR451
RNA type  microRNA
Mir-451 microRNA

In molecular biology mir-451 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.

miR-451 regulates the drug-transporter protein P-glycoprotein, potentially promoting resistance to the chemotherapy drug Paclitaxel.

Applications

A proof-of-concept experiment has shown that miR-451, as well as mir-126 and mir-150, could be using in forensic science to distinguish between blood and saliva samples. This is made possible by different miRNA profiles of miRNAs in the different tissue types.

References

Mir-451 microRNA Wikipedia


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