Symbol mir-451 miRBase family MIPF0000148 OMIM 612071 | Rfam RF00722 HUGO MIR451 | |
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In molecular biology mir-451 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.
miR-451 regulates the drug-transporter protein P-glycoprotein, potentially promoting resistance to the chemotherapy drug Paclitaxel.
Applications
A proof-of-concept experiment has shown that miR-451, as well as mir-126 and mir-150, could be using in forensic science to distinguish between blood and saliva samples. This is made possible by different miRNA profiles of miRNAs in the different tissue types.
References
Mir-451 microRNA Wikipedia(Text) CC BY-SA