Citizenship Canadian | Field Biochemistry | |
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Born September 14, 1958 (age 58) ( 1958-09-14 ) Fields Biochemistry and molecular pharmacology Notable awards Fellow of the Academy of Science of the Royal Society of Canada/ Fellow of the Canadian Academy of Health Sciences / Canada Research Chair in Signal Transduction and Molecular Pharmacology | ||
Intervention du professeur michel bouvier les enjeux de la fiscalit partie 1
Michel Bouvier (born September 14, 1958) is a Canadian biochemist and molecular pharmacologist. He is a professor of biochemistry and molecular medicine at Université de Montréal; a principal investigator and the Chief Executive Officer at the Institute for Research in Immunology and Cancer; and an Associate Vice-President in Research, Scientific Discovery, Creation and Innovation at Université de Montréal. His work focuses on the study of cell signaling towards the discovery of new pharmaceutical drugs.
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Intervention du professeur michel bouvier partie 2
Biography
Michel Bouvier earned a B.Sc. in Biochemistry (1979) and a Ph.D. in Neurological Sciences (1985) from Université de Montréal, and then completed a post-doctoral fellow (1985-1989) at Duke University under the supervision of Dr. Robert J. Lefkowitz (2012 Nobel Prize in Chemistry). Bouvier is a professor in the Department of Biochemistry and Molecular Medicine at the Faculty of Medicine of Université de Montréal and a principal investigator at the Institute for Research in Immunology and Cancer (IRIC) at Université de Montréal.
Research
He is a world-known expert in cell signaling and drug discovery, notably in the field of G protein-coupled receptors (GPCRs). GPCRs constitute the largest single protein family involved in the transduction of hormonal signals and neurotransmitters. Their physiological significance makes them a prime target in drug development, and over a third of existing drugs use GPCRs as their target site of action. Bouvier’s work in the regulation of receptors led to new paradigms (inverse agonism; pharmacological chaperones; receptor polymerization; and pluri-dimensionality of signaling), which, coupled with the development of bioluminescence resonance energy transfer (BRET)-based methods, have a direct impact on drug discovery. He has authored over 260 scientific articles, filed 36 patent applications, and delivered over 400 lectures as a guest lecturer. Bouvier holds the Canada Research Chair in Signal Transduction and Molecular Pharmacology