| Nuevo León, Coahuila|| 521.6 km|
| Fed. 85 near Apodaca, N.L.|
Boquillas del Carmen near Mexico – United States border
Federal Highway 53 (Carretera Federal 53) connects metropolitan Monterrey, Nuevo León to Boquillas del Carmen, Coahuila near the Mexico–United States border.
Southern terminus at Fed. 85 near Apodaca, N.L.
Fed. 38 in General Escobedo
Fed. 57 near Castaños, Coah.
Fed. 30 in Monclova
Fed. 57 in Nueva Rosita
Mexican Federal Highway 53 Wikipedia
The northern terminus is at Boquillas del Carmen near the Mexico–United States border along the Rio Grande.