Methylglyoxal reductase (NADPH dependent)

In enzymology, a methylglyoxal reductase (NADPH-dependent) (EC 1.1.1.283) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are lactaldehyde and NADP⁺, whereas its 3 products are methylglyoxal, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is lactaldehyde:NADP⁺ oxidoreductase. Other names in common use include lactaldehyde dehydrogenase (NADP⁺), and Gre2.