ATC code None PubChem CID 3032307 ChEMBL CHEMBL2104624 Molar mass 288.429 g/mol | CAS Number 467-43-6 ChemSpider 2297317 Formula C12H20N2O2S2 | |
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How to pronounce methitural
Methitural (INN; Neraval, Thiogenal), or methitural sodium, also known as methioturiate, is a barbiturate derivative which was marketed in the 1950s in Europe (in Germany and Italy) as an ultra-short-acting intravenous anesthetic.
Contents
Synthesis
A somewhat more complex side chain is incorporated by alkylation of the carbanion of the substituted cyanoacetate (1) with 2-chloroethylmethyl sulfide (2). Condensation of the resulting cyanoester (3) with thiourea followed by hydrolysis of the resulting imine affords methitural.
References
Methitural Wikipedia(Text) CC BY-SA