McKinstry is a surname. Notable people with the surname include:
Alexander McKinstry (1822–1879), American politician
Chris McKinstry (1967–2006), Canadian artificial intelligence researcher
Elisha W. McKinstry (1824–1901), American jurist
Henry McKinstry, Canadian mayor
James A. McKinstry (born 1942), American football player
James McKinstry (born 1979), Scottish footballer
John McKinstry, Canadian musician and singer
Leo McKinstry (born 1962), Northern Irish writer and journalist
Nancy McKinstry (born 1959), American businesswoman