McClain (Gaelic: Mac Gill-Eain) is a surname. Notable people with the surname include:
Albritton McClain (contemporary), American rock guitarist
Cady McClain (b. 1969), American actress
Charly McClain (b. 1956), American country music singer
China Anne McClain (b. 1998), American actress and singer, one of the 3McClainGirls and McClain Sisters
Dave McClain (coach) (b. 1938), American football coach
Dave McClain (drummer) (contemporary), American heavy metal drummer
David McClain (president) (contemporary), American academic, President of the University of Hawaii
Dewey McClain, American football player, politician from Georgia
Dwayne McClain (b. 1973), American professional basketball player
Edward McClain (b. 1944), American politician from Alabama
Frank B. McClain (1864–1925), American politician from Pennsylvania
Jimmy McClain (b. 1980), American football player
Johnathan McClain (contemporary), American stage and television actor
Lauryn McClain (b. 1997), American actress and singer, one of the 3McClainGirls and McClain Sisters
Leonard MacClain (1899-1967), American organist
Le'Ron McClain (b. 1984), American professional football player
Leanita McClain (1951–1984), American journalist and commentator
Michael Sean McClain (b. 1975), American fencer
Patricia McClain (b. 1954), American model and Playboy centerfold
Scott McClain (b. 1972), American professional baseball player
Sierra McClain (b. 1994), American actress and singer, one of the 3McClainGirls and McClain Sisters
Steve McClain (b. 1962), American basketball coach
Ted McClain (b. 1946), American professional basketball player
Thaddeus McClain (1876–1935), American track and field Olympic athlete
Fictional people:
Paul McClain, character in the Australian soap opera Neighbours
Shauni McClain, character in the American TV series Baywatch
