Manukyan (Armenian: Մանուկյան) is an Armenian surname. It can refer to the following people:
Aghasi Manukyan, an Armenian wrestler
Arman Manukyan, a professor of Boğaziçi University
Edward Manukyan, an Armenian-American composer
Matild Manukyan, an Armenian-Turkish businesswoman
Mkhitar Manukyan, an Armenian-Kazakhstani wrestler
Sergey Manukyan, a jazz musician
Vazgen Manukyan, a former Prime Minister of Armenia
Manukian
Aram Manukian (1879–1919), also Aram of Van and Sarkis Hovanessian, an Armenian revolutionary, politician and military commander, a leader of the Van Resistance and instrumental the foundation of the First Republic of Armenia in 1918
Manoukyan
Sargis Manoukyan, founding member of the Armenian rock band Empyray
