Mackie /ˈmæki/ is a surname. Notable people with the surname include:
Alec Mackie (1903–1984), Irish footballer with Arsenal F.C. and Portsmouth F.C.
Alex Mackie (1870–unknown), Scottish football manager with Middlesbrough F.C.
Andrew Mackie (born 1984), Australian rules footballer with the Geelong Football Club
Anthony Mackie (born 1978), American actor
Bob Mackie (born 1940), American fashion designer
Calvin Mackie (born 1969), American entrepreneur (son of Anthony Mackie)
Charles Mackie (Scottish footballer) (1882–unknown), played for Aberdeen, West Ham United and Manchester United
Charles Mackie (New Zealand footballer), New Zealand international footballer in the 1930s
Cloe and Holly Mackie (born 1997), twin British actresses
Craig Mackie (born 1950), Canadian curler and radio and television personality
Darren Mackie (born 1982), Scottish footballer with Aberdeen F.C.
David Mackie (1836–1910), a founder and builder of Scammon, Kansas, US; the first President of the Scammon State Bank
Gael Mackie (born 1988), Canadian gymnast and Olympic athlete
Greg Mackie Australian arts promoter
Greg Clark Mackie (born 1949) American audio engineer and inventor
Howard Mackie (born 1958), American comic book editor and writer
Jamie Mackie (born 1985), English footballer with Queens Park Rangers
Jason Mackie (born 1968), New Zealand rugby league player
Jerry Mackie (1894–1959), Scottish footballer with Portsmouth F.C. and Southampton F.C.
John Mackie (disambiguation), several people
John Leslie Mackie (1917–1981), Australian philosopher
Lise Mackie (born 1975), Australian freestyle swimmer
Neil Mackie (born 1946), Scottish tenor and professor of music
Osbert Mackie (1868–1927), English rugby union player
Pat Mackie (1914–2009), New Zealand miner and unionist
Penelope Mackie, British academic
Sir Peter Mackie (1855–1924), a Scottish whisky distiller
Peter Mackie (footballer) (born 1958), Scottish footballer
Philip Mackie (1918–1985), British film and television screenwriter
Samuel Joseph Mackie (1823–1902), British geologist, inventor, and editor
Thomas Mackie (disambiguation), several people
William Mackie, several people