Entrez 4618 | Ensembl ENSG00000111046 | |
Aliases MYF6, CNM3, MRF4, bHLHc4, myf-6, Myf6, myogenic factor 6 External IDs MGI: 97253 HomoloGene: 1850 GeneCards: MYF6 | ||
Myogenic factor 6 (herculin) is a protein that in humans is encoded by the MYF6 gene. Also known in the medical literature as MRF4 and herculin), MYF6 is a myogenic regulatory factor (MRF) in the process known as myogenesis.
Contents
Function
MYF6 is a member of the myogenic factors (MYF) family that regulate myogenesis and muscle regeneration. Myogenic factor are basic helix-loop-helix (bHLH) transcription factors. Defects in this gene are a cause of autosomal dominant centronuclear myopathy (ADCNM).
Clinical significance
Mutations in the MYF6 gene are associated with myopathy.
References
MYF6 Wikipedia(Text) CC BY-SA