Species Human Entrez 4605 | Human Mouse Ensembl ENSG00000101057 | |
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Aliases MYBL2, B-MYB, BMYB, MYB proto-oncogene like 2 External IDs MGI: 101785 HomoloGene: 1847 GeneCards: MYBL2 | ||
Myb-related protein B is a protein that in humans is encoded by the MYBL2 gene.
Contents
Function
The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.
Interactions
MYBL2 has been shown to interact with:
References
MYBL2 Wikipedia(Text) CC BY-SA