Trisha Shetty (Editor)

MX2

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Species
  
Human

Entrez
  
4600

Human
  
Mouse

Ensembl
  
ENSG00000183486

MX2

Aliases
  
MX2, MXB, MX dynamin like GTPase 2

External IDs
  
HomoloGene: 74299 GeneCards: MX2

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For the aircraft and other subjects see MX2 (disambiguation)

Interferon-induced GTP-binding protein Mx2 is a protein that in humans is encoded by the MX2 gene.

Contents

The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1.

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References

MX2 Wikipedia