Symbol MT-TK Entrez 4566 RefSeq NC_001807 | Alt. symbols MERRF, MTTK HUGO 7489 Locus Chr. MT [1] | |
Mitochondrially encoded tRNA lysine also known as MT-TK is a transfer RNA which in humans is encoded by the mitochondrial MT-TK gene.
Contents
Function
MT-TK is a small 70 nucleotide RNA (human mitochondrial map position 8295-8364) that transfers the amino acid lysine to a growing polypeptide chain at the ribosome site of protein synthesis during translation.
Clinical significance
Mutations in the MT-TK gene are associated with myoclonic epilepsy and ragged-red fiber disease (MERRF).
References
MT-TK Wikipedia(Text) CC BY-SA