Girish Mahajan (Editor)

MRC 5

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MRC-5 (Medical Research Council cell strain 5) is a diploid human cell culture line composed of fibroblasts derived from lung tissue of an 14 week old aborted caucasian male fetus. The cell line was isolated by J.P. Jacobs and colleagues in September 1966.

Applications

MRC-5 cells are used to produce several vaccines including MMR, Varicella and Polio. Infected MRC-5 cells secrete the virus, and can be cultured in large volumes suitable for commercial production.

References

MRC-5 Wikipedia