Symbol MDGA2 Entrez 161357 OMIM 611128 | Alt. symbols MAMDC1 HUGO 19835 RefSeq NM_182830 | |
MDGA2 (MAM domain containing glycosylphosphatidylinositol anchor 2) is a human gene. It has previously been called MAMDC1. MDGA2 is located on chromosome 14.
The gene has a homologue in rat and mouse, Mdga2, and investigations in rats have found that the gene is expressed in the central and peripheral nervous system in a subpopulation of neurons, e.g., in the basilar pons and cerebral cortex.
There are several variants in the human gene, and a genome-wide association study has pointed to that single-nucleotide polymorphisms in MDGA2 is associated with neuroticism.
References
MDGA2 Wikipedia(Text) CC BY-SA