Suvarna Garge (Editor)

MAST2

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Species
  
Human

Entrez
  
23139

Human
  
Mouse

Ensembl
  
ENSG00000086015

MAST2

Aliases
  
MAST2, MAST205, MTSSK, microtubule associated serine/threonine kinase 2

External IDs
  
MGI: 894676 HomoloGene: 7428 GeneCards: MAST2

Microtubule-associated serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the MAST2 gene. The protein encoded by this gene controls TRAF6 and NF-kappaB activity.

Contents

Interactions

MAST2 has been shown to interact with PCLKC.

Model organisms

Model organisms have been used in the study of MAST2 function. A conditional knockout mouse line called Mast2tm1a(KOMP)Wtsi has been generated. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping

References

MAST2 Wikipedia