Species Human Entrez 2011 | Human Mouse Ensembl ENSG00000072518 | |
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Aliases MARK2, EMK-1, EMK1, PAR-1, Par-1b, Par1b, microtubule affinity regulating kinase 2 External IDs MGI: 99638 HomoloGene: 69013 GeneCards: MARK2 | ||
Serine/threonine-protein kinase MARK2 is an enzyme that in humans is encoded by the MARK2 gene.
Contents
Function
EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1. These isoforms were characterized by the presence of a 162-bp alternative exon that gave rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be coexpressed in a number of selected cell lines and tissue samples. The human EMK1 was shown to be encoded by a single mRNA ubiquitously expressed.
Interactions
MARK2 has been shown to interact with AKT1.
References
MARK2 Wikipedia(Text) CC BY-SA