Species Human Entrez 10982 | Human Mouse Ensembl ENSG00000166974 | |
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Aliases MAPRE2, EB1, EB2, RP1, CSCSC2, microtubule associated protein RP/EB family member 2 External IDs HomoloGene: 75027 GeneCards: MAPRE2 | ||
Microtubule-associated protein RP/EB family member 2 is a protein that in humans is encoded by the MAPRE2 gene.
Contents
Function
The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. The function of this protein is unknown; however, its homology suggests involvement in tumorigenesis of colorectal cancers and proliferative control of normal cells. This gene may belong to the intermediate/early gene family, involved in the signal transduction cascade downstream of the TCR.
Interactions
MAPRE2 has been shown to interact with APC.
References
MAPRE2 Wikipedia(Text) CC BY-SA