Species Human Entrez 9175 | Human Mouse Ensembl ENSG00000073803 | |
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Aliases MAP3K13, LZK, MEKK13, MLK, mitogen-activated protein kinase kinase kinase 13 External IDs MGI: 2444243 HomoloGene: 37958 GeneCards: MAP3K13 | ||
Mitogen-activated protein kinase kinase kinase 13 is an enzyme that in humans is encoded by the MAP3K13 gene.
Contents
Function
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway.
Interactions
MAP3K13 has been shown to interact with PRDX3.
References
MAP3K13 Wikipedia(Text) CC BY-SA