Supriya Ghosh (Editor)

MAGI1

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Species
  
Human

Entrez
  
9223

Human
  
Mouse

Ensembl
  
n/a

MAGI1

Aliases
  
MAGI1, AIP-3, AIP3, BAIAP1, BAP-1, BAP1, MAGI-1, Magi1d, TNRC19, WWP3, membrane associated guanylate kinase, WW and PDZ domain containing 1

External IDs
  
MGI: 1203522 HomoloGene: 31257 GeneCards: MAGI1

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 is an enzyme that in humans is encoded by the MAGI1 gene.

Contents

Function

The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell–cell contact. The product of this gene may play a role as scaffolding protein at cell–cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified.

Interactions

MAGI1 has been shown to interact with:

  • ACCN3,
  • ATN1,
  • Actinin alpha 4,
  • Beta-catenin,
  • Brain-specific angiogenesis inhibitor 1,
  • Calcium-activated potassium channel subunit alpha-1,
  • FCHSD2,
  • LRP2, and
  • SYNPO.

    • References

    MAGI1 Wikipedia
    (Text) CC BY-SA