Lykke is a surname. Notable people with the surname include:
Anne Lykke (1595–1641), Danish noblewoman and royal mistress of Christian, Prince Elect of Denmark
Ivar Lykke (politician) (1872–1949), Norwegian politician; Prime Minister of Norway, 1926–1928
Ivar Lykke (footballer) (1889–1955), Danish amateur footballer
Ivar Lykke (architect) (born 1941), Norwegian architect
Lykke Li (born Li Lykke, 1986), Swedish singer-songwriter
Nina Lykke (born 1949), Swedish professor of gender studies at Linköping University
Sophie Lykke (d. 1570), Danish county administrator, landholder and noble
