Lupo is a surname of Italian origin, meaning "wolf", which is derived from the Latin lupus. Its Spanish equivalent is López, its Portuguese equivalent is Lopes, its French equivalent is Loup, and its Romanian equivalent is Lupu or Lupescu.
The name may refer to:
Persons
Alberto Lupo (1924–1984), Italian film actor
Anthony Lupo (1966-present), professor of atmospheric science at the University of Missouri
Francis Lupo (1895–1918), American soldier killed in World War I; remains recovered in 2003 in France
Frank Lupo (contemporary), American television writer and producer
Janet Lupo (b. 1950), American model; Playboy Playmate 1975
Michael Lupo (1953–1995), Italian serial killer in the UK
Family
Lupo family, A family of court musicians in England in the 16th and 17th centuries
Fictional characters
Cyrus Lupo, character on the American television series Law & Order
Jo Lupo, character on the American television series Eureka